|
Discovery of new targets for treatment of the Parkinson disease
Key words: drug discovery, brain disease.
Consortium
- Companies: Euroscreen (Coordinator)
- Research centers: ULB (IRIBHM & ULB-Neurophysiology), FUNDP , Certech
Topic of the project
The aim of the HOPE 4 PD project is to:
- Validate two G protein coupled receptors (GPCRs) the expression of which is modified in striatum of patients with Parkinson's disease, as targets of drugs for the treatment of neuro-degenerative diseases, Parkinson's disease being the first indication.
- Identify original compounds able to modulate the activity of these receptors and allow the initiation of an innovating program of drug discovery for Parkinson's disease, up to the development of original chemical molecules and the demonstration of efficacy in animal models.
Such a project is made possible by setting up a Walloon consortium involving 5 partners, academic and industrial, whose expertise and combined know how will make it possible to cover all the aspects of the Project, from the discovery and the validation of target up to the development of drugs.
Budget
This is a 4-year project with a total budget of M€ 4.5.
Contact
Thierry Ferain (Coordinator of the project)
Email: tferain@euroscreen.com
EUROSCREEN SA
Website: http://www.euroscreen.com
|
|
|
|