Tools and methods towards the exploitation of a cyclotron-based hadrontherapy facility

Key words: medical device and equipment, hadrontherapy, treatment planning, quality assurance, primary dosimetry, calorimetry, optimisation.


  • Companies: IBA (Coordinator), QSPIN
  • Research centers: UCL /IMRE , Centre d’Expertise en Aéronautique (Cenaro)
  • International research centers: Instituto Nazionale de Fisica Nucleare (INFN, Italy), Mc Gill University Hospital  (Canada), Centre de Ressources en Hadronthérapie (Archade, France), National Physics Lab (NPL,UK)

Topic of the project

Hadrontherapy aims at treating cancers by irradiating tumor cells with protons or light ions (carbon), offering increased precision and significant biological gain on specific tumor cases.
IBA is designing a new machine capable of treating patients with protons and carbon ions. This technical programme must be completed by additional research activities to provide the tools needed to compute the treatment parameters, and to perform the necessary quality checks before delivering the radiation to the patients.

The contributions brought through WinTPS include:
  • The development of an absolute dosimeter, to be used as a primary reference for the conventional dosimetry tools to be used on any hadrontherapy centre.
  • Methodological support to guarantee that the treatment planning software (developed by IBA in collaboration with Italian research labs) rely on a robust architecture and follow the appropriate quality standards;
  • Radiobiology experiments that will accumulate sets of measured data to benchmark the radiobiological models implemented in the planning software;
  • The development of an optimization library based on powerful algorithms, that  will speed up the computation of treatment plans and enhance their intrinsic qualities and matching with equipment parameters.      


This is a 4-year project with a total budget of M€ 2.5.


Damien Bertrand (Coordinator of the project)